12(S)‐hydroxyeicosatetraenoic acid impairs vascular endothelial permeability by altering adherens junction phosphorylation levels and affecting the binding and dissociation of its components in high glucose‐induced vascular injury

12(S)‐hydroxyeicosatetraenoic acid impairs vascular endothelial permeability by altering adherens junction phosphorylation levels and affecting the binding and dissociation of its components in high glucose‐induced vascular injury

Abstract Aims/Introduction Diabetes is an important risk factor for atherosclerotic disease. The initiating factor of atherosclerosis is local endothelial cell injury. The arachidonic acid metabolite, 12(S)‐hydroxyeicosatetraenoic acid (12[S]‐HETE), might be involved in this process. In recent years...

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Bibliographic Details
Main Authors: Xiaofang Wang, Lu Gao, Lili Xiao, Lulu Yang, Wenshu Li, Gangqiong Liu, Linlin Chen, Jinying Zhang
Format: Article
Language:English
Published: Wiley 2019-05-01
Series:Journal of Diabetes Investigation
Subjects:
12(S)‐hydroxyeicosatetraenoic acid
Endothelial permeability
High glucose
Online Access:https://doi.org/10.1111/jdi.12941

Internet

https://doi.org/10.1111/jdi.12941

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