Characterization of Three Pleiotropic Drug Resistance Transporter Genes and Their Participation in the Azole Resistance of Mucor circinelloides

Characterization of Three Pleiotropic Drug Resistance Transporter Genes and Their Participation in the Azole Resistance of Mucor circinelloides

Mucormycosis is a life-threatening opportunistic infection caused by certain members of the fungal order Mucorales. This infection is associated with high mortality rate, which can reach nearly 100% depending on the underlying condition of the patient. Treatment of mucormycosis is challenging becaus...

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Bibliographic Details
Main Authors: Gábor Nagy, Sándor Kiss, Rakesh Varghese, Kitti Bauer, Csilla Szebenyi, Sándor Kocsubé, Mónika Homa, László Bodai, Nóra Zsindely, Csaba Vágvölgyi, Tamás Papp
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Mucor
pleiotropic drug resistance
CRISPR-Cas9
azole
ABC transporter
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.660347/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2021.660347/full

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