Systematic identification of factors mediating accelerated mRNA degradation in response to changes in environmental nitrogen.

Cellular responses to changing environments frequently involve rapid reprogramming of the transcriptome. Regulated changes in mRNA degradation rates can accelerate reprogramming by clearing or stabilizing extant transcripts. Here, we measured mRNA stability using 4-thiouracil labeling in the budding...

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Bibliographic Details
Main Authors: Darach Miller, Nathan Brandt, David Gresham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5983874?pdf=render