CitE Enzymes Are Essential for Mycobacterium tuberculosis to Establish Infection in Macrophages and Guinea Pigs

CitE Enzymes Are Essential for Mycobacterium tuberculosis to Establish Infection in Macrophages and Guinea Pigs

Bacterial citrate lyase activity has been demonstrated in various eukaryotes, bacteria and archaea, underscoring their importance in energy metabolism of the cell. While the bacterial citrate lyase comprises of three different subunits, M. tuberculosis genome lacks CitD and CitF subunits of citrate...

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Bibliographic Details
Main Authors: Garima Arora, Deepika Chaudhary, Saqib Kidwai, Deepak Sharma, Ramandeep Singh
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Mycobacterium tuberculosis
reverse TCA
β-subunit of citrate lyase
virulence
oxidative stress
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2018.00385/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2018.00385/full

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