Development of an Antigen-DNAzyme Based Probe for a Direct Antibody-Antigen Assay Using the Intrinsic DNAzyme Activity of a Daunomycin Aptamer
G-Quadruplex (G-4) structures are formed when G-rich DNA sequences fold into intra- or intermolecular four-stranded structures in the presence of metal ions. G-4-hemin complexes are often effective peroxidase-mimicking DNAzymes that are applied in many detection systems. This work reports the appli...
Main Authors: | Noorsharmimi Omar, Qiuting Loh, Gee Jun Tye, Yee Siew Choong, Rahmah Noordin, Jörn Glökler, Theam Soon Lim |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-12-01
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Series: | Sensors |
Subjects: | |
Online Access: | http://www.mdpi.com/1424-8220/14/1/346 |
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