Synthesis and antiproliferative activities of polymethoxyflavones aminoalkyl and amino acid derivatives

Twelve novel aminoalkyl derivatives 3a-3f, 4a-4f and four novel amino acid derivatives 5a, 5b, 6a and 6b of polymethoxyflavones 1 and 2 were synthesized through regioselective demethylation, etherification, amination, EDCl-mediated amide condensation and alkaline hydrolysis, using tangeretin and nob...

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Bibliographic Details
Main Authors: Ran Li-qiong, Li Xue-li, Liu Man-hui, Wang Qiu-an
Format: Article
Language:English
Published: De Gruyter 2020-04-01
Series:Heterocyclic Communications
Subjects:
Online Access:http://www.degruyter.com/view/j/hc.2020.26.issue-1/hc-2020-0010/hc-2020-0010.xml?format=INT