Effects of Early and Delayed Antiretroviral Therapy on Plasma Anti-CD4 Autoreactive IgG and Its Association With CD4+ T-Cell Recovery in Acute HIV-Infected Individuals

Effects of Early and Delayed Antiretroviral Therapy on Plasma Anti-CD4 Autoreactive IgG and Its Association With CD4+ T-Cell Recovery in Acute HIV-Infected Individuals

BackgroundPlasma levels of anti-CD4 autoantibodies are increased in chronically HIV-infected patients and inversely correlated with CD4+ T-cell recovery under viral-suppressive antiretroviral therapy (ART). However, it remains unknown the effect of early ART on plasma anti-CD4 autoantibody levels in...

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Bibliographic Details
Main Authors: Aixin Song, Zhen Li, Zhenwu Luo, Xiaofan Lu, Rui Wang, Lifeng Liu, Wei Xia, Zhuang Wan, Tong Zhang, Bin Su, Wei Jiang, Hao Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Pharmacology
Subjects:
CD4+ T cells
acute HIV infection
antiretroviral therapy
autoantibody
men who had sex with men (MSM)
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00449/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00449/full

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