Evidence That Parietal Lobe Fatty Acids May Be More Profoundly Affected in Moderate Alzheimer’s Disease (AD) Pathology Than in Severe AD Pathology

Evidence That Parietal Lobe Fatty Acids May Be More Profoundly Affected in Moderate Alzheimer’s Disease (AD) Pathology Than in Severe AD Pathology

Brain is a lipid-rich tissue, and fatty acids (FAs) play a crucial role in brain function, including neuronal cell growth and development. This study used GC-MS to survey all detectable FAs in the human parietal cortex (Brodmann area 7). These FAs were accurately quantified in 27 cognitively normal...

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Bibliographic Details
Main Authors: Muhammad L. Nasaruddin, Xiaobei Pan, Bernadette McGuinness, Peter Passmore, Patrick G. Kehoe, Christian Hölscher, Stewart F. Graham, Brian D. Green
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Metabolites
Subjects:
fatty acid
GC-MS
Alzheimer’s disease
dementia with Lewy bodies
metabolomics
lipidomics
Online Access:https://www.mdpi.com/2218-1989/8/4/69

Internet

https://www.mdpi.com/2218-1989/8/4/69

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