Alveolar macrophages infected with Ames or Sterne strain of Bacillus anthracis elicit differential molecular expression patterns.

Alveolar macrophages (AMs) phagocytose Bacillus anthracis following inhalation and induce the production of pro-inflammatory cytokines and chemokines to mediate the activation of innate immunity. Ames, the virulent strain of B. anthracis, contains two plasmids that encode the antiphagocytic poly-γ-d...

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Main Authors: Felicia D Langel, Chih-Yuan Chiang, Douglas Lane, Tara Kenny, Jenifer F Ojeda, Yang Zhong, Jianwei Che, Yingyao Zhou, Wilson Ribot, Krishna P Kota, Sina Bavari, Rekha G Panchal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3917846?pdf=render