Identification of Heterogeneous Subtypes of Mild Cognitive Impairment Using Cluster Analyses Based on PET Imaging of Tau and Astrogliosis

Identification of Heterogeneous Subtypes of Mild Cognitive Impairment Using Cluster Analyses Based on PET Imaging of Tau and Astrogliosis

Background: Mild cognitive impairment (MCI) is a condition with diverse causes and clinical outcomes that can be categorized into subtypes. [18F]THK5351 has been known to detect reactive astrogliosis as well as tau which is accompanied by neurodegenerative changes. Here, we identified heterogeneous...

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Bibliographic Details
Main Authors: Hyun Jeong Lee, Eun-Chong Lee, Seongho Seo, Kwang-Pil Ko, Jae Myeong Kang, Woo-Ram Kim, Ha-Eun Seo, Sang-Yoon Lee, Yeong-Bae Lee, Kee Hyung Park, Byeong Kil Yeon, Nobuyuki Okamura, Duk L. Na, Joon-Kyung Seong, Young Noh
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
mild cognitive impairment
tau
THK
cluster analysis
positron emission tomography
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2020.615467/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2020.615467/full

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