Epstein Barr virus-induced 3 (EBI3) together with IL-12 negatively regulates T helper 17-mediated immunity to Listeria monocytogenes infection.

Although the protective functions by T helper 17 (Th17) cytokines against extracellular bacterial and fungal infection have been well documented, their importance against intracellular bacterial infection remains unclear. Here, we investigated the contribution of Th17 responses to host defense again...

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Bibliographic Details
Main Authors: Yeonseok Chung, Tomohide Yamazaki, Byung-Seok Kim, Yongliang Zhang, Joseph M Reynolds, Gustavo J Martinez, Seon Hee Chang, Hoyong Lim, Mark Birkenbach, Chen Dong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3777861?pdf=render