In search for potential antidiabetic compounds from natural sources: docking, synthesis and biological screening of small molecules from Lycium spp. (Goji)

In search for potential antidiabetic compounds from natural sources: docking, synthesis and biological screening of small molecules from Lycium spp. (Goji)

Current clinical antidiabetic drugs, like rosiglitazone 1, have been implicated in some serious side effects like edema, weight gain, and heart failure, making it necessary to find alternative agents. Partial agonists of peroxisome-proliferator activated receptor-gamma (PPARγ) were determined to pos...

Full description

Bibliographic Details
Main Authors: Chinni Yalamanchili, Amar G. Chittiboyina, Saqlain Haider, Yelkaira Vasquez, Shabana Khan, Jussara M. do Carmo, Alexandre A. da Silva, Mark Pinkerton, John E. Hall, Larry A. Walker, Ikhlas A. Khan
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Heliyon
Subjects:
Natural product chemistry
Organic chemistry
Pharmaceutical chemistry
Diabetes mellitus
Wolfberry
Cercosporamide
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844019364424

Internet

http://www.sciencedirect.com/science/article/pii/S2405844019364424

Similar Items