Unmasking activation of the zygotic genome using chromosomal deletions in the Drosophila embryo.

During the maternal-to-zygotic transition, a developing embryo integrates post-transcriptional regulation of maternal mRNAs with transcriptional activation of its own genome. By combining chromosomal ablation in Drosophila with microarray analysis, we characterized the basis of this integration. We...

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Bibliographic Details
Main Authors: Stefano De Renzis, Olivier Elemento, Saeed Tavazoie, Eric F Wieschaus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-05-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1854917?pdf=render