PPARα and PPARγ activators suppress the monocyte-macrophage apoB-48 receptor1

PPARα and PPARγ activators suppress the monocyte-macrophage apoB-48 receptor1

Certain triglyceride-rich lipoproteins (TRLs), specifically chylomicrons, dyslipemic VLDLs, and their remnants, are atherogenic and can induce monocyte-macrophage foam cell formation in vitro via the apolipoprotein B-48 receptor (apoB-48R). Human atherosclerotic lesion foam cells express the apoB-48...

Full description

Bibliographic Details
Main Authors: Go Haraguchi, Yasushi Kobayashi, Matthew L. Brown, Akira Tanaka, Mitsuaki Isobe, Sandra H. Gianturco, William A. Bradley
Format: Article
Language:English
Published: Elsevier 2003-06-01
Series:Journal of Lipid Research
Subjects:
lipoproteins
triglyceride
atherosclerosis
apolipoprotein B
foam cells
peroxisome proliferator-activated receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752031124X

Internet

http://www.sciencedirect.com/science/article/pii/S002222752031124X

Similar Items