Gene profile of myeloid-derived suppressive cells from the bone marrow of lysosomal acid lipase knock-out mice.

Gene profile of myeloid-derived suppressive cells from the bone marrow of lysosomal acid lipase knock-out mice.

Lysosomal acid lipase (LAL) controls development and homeostasis of myeloid lineage cells. Loss of the lysosomal acid lipase (LAL) function leads to expansion of myeloid-derived suppressive cells (MDSCs) that cause myeloproliferative neoplasm.Affymetrix GeneChip microarray analysis identified detail...

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Bibliographic Details
Main Authors: Cong Yan, Xinchun Ding, Nupur Dasgupta, Lingyan Wu, Hong Du
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3288004?pdf=render

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http://europepmc.org/articles/PMC3288004?pdf=render

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