Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine
Using a Streptococcus pneumoniae human challenge model, the authors here show that baseline nasal microbiota profiles are associated with pneumococcal acquisition and density, independent of live-attenuated influenza vaccine (LAIV) administration, and with mucosal cytokine responses to LAIV.
Main Authors: | , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-07-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-10814-9 |