Individual co-variation between viral RNA load and gene expression reveals novel host factors during early dengue virus infection of the Aedes aegypti midgut.

Individual co-variation between viral RNA load and gene expression reveals novel host factors during early dengue virus infection of the Aedes aegypti midgut.

Dengue virus (DENV) causes more human infections than any other mosquito-borne virus. The current lack of antiviral strategies has prompted genome-wide screens for host genes that are required for DENV infectivity. Earlier transcriptomic studies that identified DENV host factors in the primary vecto...

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Bibliographic Details
Main Authors: Vincent Raquin, Sarah Hélène Merkling, Valérie Gausson, Isabelle Moltini-Conclois, Lionel Frangeul, Hugo Varet, Marie-Agnès Dillies, Maria-Carla Saleh, Louis Lambrechts
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0006152

Internet

https://doi.org/10.1371/journal.pntd.0006152

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