Elevated whole muscle phosphatidylcholine: phosphatidylethanolamine ratio coincides with reduced SERCA activity in murine overloaded plantaris muscles

Abstract Background An increase in phosphatidylcholine:phosphatidylethanolamine (PC:PE) and a decrease in fatty acyl chain length, monounsaturated:polyunsaturated (MUFA:PUFA) fatty acyl ratio reduces SERCA activity in liposomes and in mouse models of obesity and muscular dystrophy. We have previousl...

Full description

Bibliographic Details
Main Authors: Val A. Fajardo, John S. Mikhaeil, Cameron F. Leveille, A. Russell Tupling, Paul J. LeBlanc
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Lipids in Health and Disease
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12944-018-0687-7