Circular RNA circNRIP1 acts as a microRNA-149-5p sponge to promote gastric cancer progression via the AKT1/mTOR pathway

Abstract Background CircRNA has emerged as a new non-coding RNA that plays crucial roles in tumour initiation and development. ‘MiRNA sponge’ is the most reported role played by circRNAs in many tumours. The AKT/mTOR axis is a classic signalling pathway in cancers that sustains energy homeostasis th...

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Bibliographic Details
Main Authors: Xing Zhang, Sen Wang, Haixiao Wang, Jiacheng Cao, Xiaoxu Huang, Zheng Chen, Penghui Xu, Guangli Sun, Jianghao Xu, Jialun Lv, Zekuan Xu
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Molecular Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12943-018-0935-5