A powerful microbial group association test based on the higher criticism analysis for sparse microbial association signals

A powerful microbial group association test based on the higher criticism analysis for sparse microbial association signals

Abstract Background In human microbiome studies, it is crucial to evaluate the association between microbial group (e.g., community or clade) composition and a host phenotype of interest. In response, a number of microbial group association tests have been proposed, which account for the unique feat...

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Bibliographic Details
Main Authors: Hyunwook Koh, Ni Zhao
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Microbiome
Subjects:
Microbiome association studies
Microbial ecology
Adaptive association analysis
Higher criticism
Sparse microbial associations
Phylogenetics
Online Access:http://link.springer.com/article/10.1186/s40168-020-00834-9

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http://link.springer.com/article/10.1186/s40168-020-00834-9

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