IL-23 receptor deficiency results in lower bone mass via indirect regulation of bone formation

IL-23 receptor deficiency results in lower bone mass via indirect regulation of bone formation

Abstract The IL-23 receptor (IL-23R) signaling pathway has pleiotropic effects on the differentiation of osteoclasts and osteoblasts, since it can inhibit or stimulate these processes via different pathways. However, the potential role of this pathway in the regulation of bone homeostasis remains el...

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Bibliographic Details
Main Authors: Wida Razawy, Celso H. Alves, Marijke Koedam, Patrick S. Asmawidjaja, Adriana M. C. Mus, Mohamed Oukka, Pieter J. M. Leenen, Jenny A. Visser, Bram C. J. van der Eerden, Erik Lubberts
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89625-2

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https://doi.org/10.1038/s41598-021-89625-2

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