Application of Molecular Topology for the Prediction of Reaction Yields and Anti-Inflammatory Activity of Heterocyclic Amidine Derivatives

Application of Molecular Topology for the Prediction of Reaction Yields and Anti-Inflammatory Activity of Heterocyclic Amidine Derivatives

Topological-mathematical models based on multiple linear regression analyses have been built to predict the reaction yields and the anti-inflammatory activity of a set of heterocylic amidine derivatives, synthesized under environmental friendly conditions, using microwave irradiation. Two models wit...

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Bibliographic Details
Main Authors: Ramón García-Domenech, María Gálvez-Llompart, Jorge Gálvez, Jordi Pla-Franco
Format: Article
Language:English
Published: MDPI AG 2011-02-01
Series:International Journal of Molecular Sciences
Subjects:
QSAR analysis
molecular topology
multilineal regression analysis
amidine derivatives
yield reaction
anti-inflammatory activity
Online Access:http://www.mdpi.com/1422-0067/12/2/1281/

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http://www.mdpi.com/1422-0067/12/2/1281/

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