Functional Genetic Variants in <i>ATG10</i> Are Associated with Acute Myeloid Leukemia

Functional Genetic Variants in <i>ATG10</i> Are Associated with Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is the most common acute leukemia, characterized by a heterogeneous genetic landscape contributing, among others, to the occurrence of metabolic reprogramming. Autophagy, a key player on metabolism, plays an essential role in AML. Here, we examined the association of thr...

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Bibliographic Details
Main Authors: Isabel Castro, Belém Sampaio-Marques, Anabela C. Areias, Hugo Sousa, Ângela Fernandes, José Manuel Sanchez-Maldonado, Cristina Cunha, Agostinho Carvalho, Juan Sainz, Paula Ludovico
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
acute myeloid leukemia
ATG10
autophagy
single nucleotide polymorphism
Online Access:https://www.mdpi.com/2072-6694/13/6/1344

Internet

https://www.mdpi.com/2072-6694/13/6/1344

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