Proteases and Protease Inhibitors of Urinary Extracellular Vesicles in Diabetic Nephropathy

Diabetic nephropathy (DN) is one of the major complications of diabetes mellitus (DM), leads to chronic kidney disease (CKD), and, ultimately, is the main cause for end-stage kidney disease (ESKD). Beyond urinary albumin, no reliable biomarkers are available for accurate early diagnostics. Urinary e...

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Bibliographic Details
Main Authors: Luca Musante, Dorota Tataruch, Dongfeng Gu, Xinyu Liu, Carol Forsblom, Per-Henrik Groop, Harry Holthofer
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2015/289734