Smad7 and Colorectal Carcinogenesis: A Double-Edged Sword

Colorectal carcinogenesis is a complex process in which many immune and non-immune cells and a huge number of mediators are involved. Among these latter factors, Smad7, an inhibitor of the transforming growth factor (TGF)-β1 signaling that has been involved in the amplification of the infla...

Full description

Bibliographic Details
Main Authors: Edoardo Troncone, Giovanni Monteleone
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/5/612