SLC35B4, an Inhibitor of Gluconeogenesis, Responds to Glucose Stimulation and Downregulates Hsp60 among Other Proteins in HepG2 Liver Cell Lines

SLC35B4, an Inhibitor of Gluconeogenesis, Responds to Glucose Stimulation and Downregulates Hsp60 among Other Proteins in HepG2 Liver Cell Lines

SLC35B4, solute receptor for UDP-N-acetylglucosamine and UDP-xylose, is associated with diabetes and predisposing conditions. This study investigated the localization of SLC35B4 and compared the differential expression between a knockdown of SLC35B4 and controls in HepG2. Responsiveness to glucose,...

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Bibliographic Details
Main Authors: Brigitte Wex, Rémi M. Safi, Gregory Antonios, Perla Z. Zgheib, Dania B. Awad, Firas H. Kobeissy, Rami A. Mahfouz, Marwan M. El-Sabban, Soha N. Yazbek
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Molecules
Subjects:
solute receptor
gluconeogenesis
downstream effect
HSP60
mass spectrometry
protein analysis
diabetes
Online Access:http://www.mdpi.com/1420-3049/23/6/1350

Internet

http://www.mdpi.com/1420-3049/23/6/1350

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