Listeriolysin O Regulates the Expression of Optineurin, an Autophagy Adaptor That Inhibits the Growth of Listeria monocytogenes

Autophagy, a well-established defense mechanism, enables the elimination of intracellular pathogens including Listeria monocytogenes. Host cell recognition results in ubiquitination of L. monocytogenes and interaction with autophagy adaptors p62/SQSTM1 and NDP52, which target bacteria to autophagoso...

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Bibliographic Details
Main Authors: Madhu Puri, Luigi La Pietra, Mobarak Abu Mraheil, Rudolf Lucas, Trinad Chakraborty, Helena Pillich
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/9/9/273