The role of DOCK10 in the regulation of the transcriptome and aging
DOCK10, a guanine-nucleotide exchange factor (GEF) for Rac1 and Cdc42 Rho GTPases whose expression is induced by interleukin-4 (IL-4) in B cells, is involved in B cell development and function according to recent studies performed in Dock10-knockout (KO) mice. To investigate whether DOCK10 is involv...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-03-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844018355452 |