A new and facile synthetic approach to substituted 2-thioxoquinazolin-4-ones by the annulation of a pyrimidine derivative

A new and facile synthesis of 2-thioxoquinazolin-4-ones by introducing a benzenoid system in the pyrimidine moiety by reacting ethoxymethylene derivatives of 1,3-diarylthiobarbituric acids (DTBA) with active methylene compounds, such as malononitrile and ethyl cyanoacetate, in presence of ZnCl2 has...

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Bibliographic Details
Main Authors: Nimalini D. Moirangthem, Warjeet S. Laitonjam
Format: Article
Published: Beilstein-Institut 2010-11-01
Series:Beilstein Journal of Organic Chemistry
Online Access:https://doi.org/10.3762/bjoc.6.120