CD133 mRNA-Loaded Dendritic Cell Vaccination Abrogates Glioma Stem Cell Propagation in Humanized Glioblastoma Mouse Model

Cancer stem cells are initiating cells of cancer and propagate its growth through self-renewal and differentiation of its daughter cells. CD133 is a cell surface antigen that is present on glioma stem cells and has been used to prospectively isolate glioma stem cells. We hypothesized that a major hi...

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Bibliographic Details
Main Authors: Angelique Sao-Mai Sy Do, Takayuki Amano, Lincoln A. Edwards, Lei Zhang, Mariza De Peralta-Venturina, John S. Yu
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Therapy: Oncolytics
Subjects:
GBM
Online Access:http://www.sciencedirect.com/science/article/pii/S237277052030098X