Identification of peptides that specifically bind Aβ1–40 amyloid in vitro and amyloid plaques in Alzheimer's disease brain using phage display
The accumulation of the amyloid-β (Aβ) peptides in amyloid plaques correlates with pathologic changes that occur in the brains of patients with Alzheimer's disease (AD). The ability to directly target reagents to the amyloid form of the Aβ peptide may allow the delivery of neuroprotective agent...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2003-10-01
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| Series: | Neurobiology of Disease |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996103001050 |