Drug Nanorod-Mediated Intracellular Delivery of microRNA-101 for Self-sensitization via Autophagy Inhibition

Drug Nanorod-Mediated Intracellular Delivery of microRNA-101 for Self-sensitization via Autophagy Inhibition

Abstract Autophagy is closely related to the drug resistance and metastasis in cancer therapy. Nanoparticle-mediated co-delivery of combinatorial therapy with small-molecular drugs and nucleic acids is promising to address drug resistance. Here, a drug-delivering-drug (DDD) platform consisting of an...

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Bibliographic Details
Main Authors: Xiaofei Xin, Xiaoqing Du, Qingqing Xiao, Helena S. Azevedo, Wei He, Lifang Yin
Format: Article
Language:English
Published: SpringerOpen 2019-09-01
Series:Nano-Micro Letters
Subjects:
Nanocrystals
MicroRNA delivery
Autophagy inhibition
Cytotoxicity
Combinatorial therapy
Online Access:http://link.springer.com/article/10.1007/s40820-019-0310-0

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http://link.springer.com/article/10.1007/s40820-019-0310-0

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