GUIDEseq: a bioconductor package to analyze GUIDE-Seq datasets for CRISPR-Cas nucleases

GUIDEseq: a bioconductor package to analyze GUIDE-Seq datasets for CRISPR-Cas nucleases

Abstract Background Genome editing technologies developed around the CRISPR-Cas9 nuclease system have facilitated the investigation of a broad range of biological questions. These nucleases also hold tremendous promise for treating a variety of genetic disorders. In the context of their therapeutic...

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Bibliographic Details
Main Authors: Lihua Julie Zhu, Michael Lawrence, Ankit Gupta, Hervé Pagès, Alper Kucukural, Manuel Garber, Scot A. Wolfe
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Genomics
Subjects:
Genome editing
CRISPR
GUIDE-seq
Off-targets analysis
Bioconductor
Online Access:http://link.springer.com/article/10.1186/s12864-017-3746-y

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http://link.springer.com/article/10.1186/s12864-017-3746-y

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