Glucosepane is associated with changes to structural and physical properties of collagen fibrils
Collagen glycation, and in particular the formation of advanced glycation end-product (AGE) crosslinks, plays a central role in the ageing process and in many of the long-term complications of diabetes. Glucosepane, the most abundant and relevant AGE crosslink, has been suggested to increase the sti...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-11-01
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| Series: | Matrix Biology Plus |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590028519300122 |