Expression and Clinical Utility of Transcription Factors Involved in Epithelial–Mesenchymal Transition during Thyroid Cancer Progression

Expression and Clinical Utility of Transcription Factors Involved in Epithelial–Mesenchymal Transition during Thyroid Cancer Progression

The transcription factors involved in epithelial–mesenchymal transition (EMT-TFs) silence the genes expressed in epithelial cells (e.g., E-cadherin) while inducing those typical of mesenchymal cells (e.g., vimentin). The core set of EMT-TFs comprises Zeb1, Zeb2, Snail1, Snail2, and Twist1. To date,...

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Bibliographic Details
Main Authors: Enke Baldini, Chiara Tuccilli, Daniele Pironi, Antonio Catania, Francesco Tartaglia, Filippo Maria Di Matteo, Piergaspare Palumbo, Stefano Arcieri, Domenico Mascagni, Giorgio Palazzini, Domenico Tripodi, Alessandro Maturo, Massimo Vergine, Danilo Tarroni, Eleonora Lori, Iulia Catalina Ferent, Corrado De Vito, Poupak Fallahi, Alessandro Antonelli, Simona Censi, Matteo D’Armiento, Susy Barollo, Caterina Mian, Aldo Morrone, Vito D’Andrea, Salvatore Sorrenti, Salvatore Ulisse
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Journal of Clinical Medicine
Subjects:
thyroid cancers
epithelial–mesenchymal transition
transcription factors
Twist1
Snail
Zeb
Online Access:https://www.mdpi.com/2077-0383/10/18/4076

Internet

https://www.mdpi.com/2077-0383/10/18/4076

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