Defining desirable natural product derived anticancer drug space: optimization of molecular physicochemical properties and ADMET attributes

As part of our endeavor to enhance survival of natural product derived drug candidates and to guide the medicinal chemist to design higher probability space for success in the anti cancer drug development area, we embarked on a detailed study of the property space for a collection of natural product...

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Bibliographic Details
Main Author: Deepika Singh
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2016-06-01
Series:ADMET and DMPK
Subjects:
Online Access:http://pub.iapchem.org/ojs/index.php/admet/article/view/291