Bioanalytical development and validation of liquid chromatographicâtandem mass spectrometric methods for the quantification of total and free cefazolin in human plasma and cord blood
Objectives: Cefazolin is a commonly prescribed β-lactam antibiotic for prophylaxis against skin infections following surgery, including caesarean sections. Assessment of maternal and neonatal exposure is important for correlating drug concentrations to clinical outcomes. Thus, bioanalytical methods...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-04-01
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Series: | Practical Laboratory Medicine |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352551715000062 |