Evidence for altered neurodevelopment and neurodegeneration in Wolfram syndrome using longitudinal morphometry
Abstract Wolfram syndrome is a rare disease caused by mutations in the WFS1 gene leading to symptoms in early to mid-childhood. Brain structural abnormalities are present even in young children, but it is not known when these abnormalities arise. Such information is critical in determining optimal o...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2019-04-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-019-42447-9 |