Daytime CLOCK Dephosphorylation Is Controlled by STRIPAK Complexes in Drosophila

In the Drosophila circadian oscillator, the CLOCK/CYCLE complex activates transcription of period (per) and timeless (tim) in the evening. PER and TIM proteins then repress CLOCK (CLK) activity during the night. The pace of the oscillator depends upon post-translational regulation that affects both...

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Bibliographic Details
Main Authors: Simonetta Andreazza, Sylvina Bouleau, Béatrice Martin, Annie Lamouroux, Prishila Ponien, Christian Papin, Elisabeth Chélot, Eric Jacquet, François Rouyer
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715004349