Mutational analysis of fructose-1,6-bis-phosphatase FBP1 indicates partially independent functions in gluconeogenesis and sensitivity to genotoxic stress

Mutational analysis of fructose-1,6-bis-phosphatase FBP1 indicates partially independent functions in gluconeogenesis and sensitivity to genotoxic stress

Fructose-1,6-bisphosphatase (FBP1) is a key enzyme in the evolutionary conserved pathway of gluconeogenesis. We had shown in an earlier study that FBP1 is involved in the response and sensitivity to methyl-methanesulfonate (MMS)-induced DNA damage in yeast. In the work presented here we performed an...

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Bibliographic Details
Main Authors: Ali Ghanem, Ana Kitanovic, Jinda Holzwarth, Stefan Wölfl
Format: Article
Language:English
Published: Shared Science Publishers OG 2017-02-01
Series:Microbial Cell
Subjects:
FBP1
S. cerevisiae
MMS
genotoxicity
DNA-damage
gluconeogenesis
Online Access:http://microbialcell.com/researcharticles/mutational-analysis-of-fructose-16-bis-phosphatase-fbp1-indicates-partially-independent-functions-in-gluconeogenesis-and-sensitivity-to-genotoxic-stress/

Internet

http://microbialcell.com/researcharticles/mutational-analysis-of-fructose-16-bis-phosphatase-fbp1-indicates-partially-independent-functions-in-gluconeogenesis-and-sensitivity-to-genotoxic-stress/

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