Pertactin-Deficient Bordetella pertussis, Vaccine-Driven Evolution, and Reemergence of Pertussis

Recent reemergence of pertussis (whooping cough) in highly vaccinated populations and rapid expansion of Bordetella pertussis strains lacking pertactin (PRN), a common acellular vaccine antigen, have raised the specter of vaccine-driven evolution and potential return of what was once the major kill...

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Bibliographic Details
Main Authors: Longhuan Ma, Amanda Caulfield, Kalyan K. Dewan, Eric T. Harvill
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2021-06-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/27/6/20-3850_article