MicroRNA miR-29b regulates diabetic aortic remodeling and stiffening

MicroRNA miR-29b regulates diabetic aortic remodeling and stiffening

Patients with type 2 diabetes (T2D) are threatened by excessive cardiovascular morbidity and mortality. While accelerated arterial stiffening may represent a critical mechanistic factor driving cardiovascular risk in T2D, specific therapies to contain the underlying diabetic arterial remodeling have...

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Bibliographic Details
Main Authors: Isabel N. Schellinger, Markus Wagenhäuser, Giriprakash Chodisetti, Karin Mattern, Angelika Dannert, Anne Petzold, Joanna Jakubizka-Smorag, Fabian Emrich, Josephina Haunschild, Andreas Schuster, Elisabeth Schwob, Kei Schulz, Lars Maegdefessel, Joshua M. Spin, Michael Stumvoll, Gerd Hasenfuß, Philip S. Tsao, Uwe Raaz
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
diabetes mellitus
arterial stiffness
microRNA
non-coding RNA
extracellular matrix
collagen
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121000561

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http://www.sciencedirect.com/science/article/pii/S2162253121000561

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