Development and characterization of an enhanced nonviral expression vector for electroporation cancer treatment

Nonviral plasmid DNA gene therapy represents a promising approach for the treatment of many diseases including cancer. Intracellular delivery of DNA can be achieved with the application of electroporation, which facilitates the initial transport of exogenous DNA across the cell membrane into the cyt...

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Bibliographic Details
Main Authors: Patrick F Forde, Lindsay J Hall, Mira Sadadcharam, Marcle de Kruijf, Gerald C O'Sullivan, Declan M Soden
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S232905011630078X