Monocarboxylate Transporter 4 Triggered Cell Pyroptosis to Aggravate Intestinal Inflammation in Inflammatory Bowel Disease

Monocarboxylate Transporter 4 Triggered Cell Pyroptosis to Aggravate Intestinal Inflammation in Inflammatory Bowel Disease

NLRP3 inflammasome has emerged as a crucial regulator of inflammatory bowel disease (IBD) characterized by a chronic inflammatory disease of the gastrointestinal tract. The expression of MCT4 is significantly increased in intestinal mucosal tissue of IBD, which has been identified to regulate intest...

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Bibliographic Details
Main Authors: Yaodong Wang, Xiaorong Zhou, Kejian Zou, Guanhua Chen, Ling Huang, Fangying Yang, Wenxu Pan, Hongwei Xu, Zhaohui Xu, Huan Chen, Jiayu Chen, Sitang Gong, Xuan Zhou, Wanfu Xu, Junhong Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
MCT4
caspase-1
cell pyroptosis
inflammatory bowel disease
NF-κB
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.644862/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.644862/full

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