Folate-Dependent Cognitive Impairment Associated With Specific Gene Networks in the Adult Mouse Hippocampus

Short-term folate deficiency has been linked to cognitive defects. Given folate's role in regulating nucleotide synthesis and DNA and histone methylation, these changes are often linked to altered gene expression and might be controlled by specific regulatory networks. In our study we examined...

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Bibliographic Details
Main Authors: Abigail Lawton, Caroline R. Morgan, Caleb R. Schreiner, Chris G. Schreiner, Jacqueline Baumann, Britton Upchurch, Feifan Xu, Michael S. Price, Gary D. Isaacs
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Nutrition
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2020.574730/full