Integrin Binding Dynamics Modulate Ligand-Specific Mechanosensing in Mammary Gland Fibroblasts

Integrin Binding Dynamics Modulate Ligand-Specific Mechanosensing in Mammary Gland Fibroblasts

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Summary: The link between integrin activity regulation and cellular mechanosensing of tissue rigidity, especially on different extracellular matrix ligands, remains poorly understood. Here, we find that primary mouse mammary gland stromal fibroblasts (MSFs) are able to spread efficiently, generate h...

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Bibliographic Details
Main Authors: Martina Lerche, Alberto Elosegui-Artola, Jenny Z. Kechagia, Camilo Guzmán, Maria Georgiadou, Ion Andreu, Donald Gullberg, Pere Roca-Cusachs, Emilia Peuhu, Johanna Ivaska
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220300912

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http://www.sciencedirect.com/science/article/pii/S2589004220300912

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