Detection of histone acetylation levels in the dorsal hippocampus reveals early tagging on specific residues of H2B and H4 histones in response to learning.

Detection of histone acetylation levels in the dorsal hippocampus reveals early tagging on specific residues of H2B and H4 histones in response to learning.

The recent literature provides evidence that epigenetic mechanisms such as DNA methylation and histone modification are crucial to gene transcription linked to synaptic plasticity in the mammalian brain--notably in the hippocampus--and memory formation. We measured global histone acetylation levels...

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Bibliographic Details
Main Authors: Olivier Bousiges, Romain Neidl, Monique Majchrzak, Marc-Antoine Muller, Alexandra Barbelivien, Anne Pereira de Vasconcelos, Anne Schneider, Jean-Philippe Loeffler, Jean-Christophe Cassel, Anne-Laurence Boutillier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3587615?pdf=render

Internet

http://europepmc.org/articles/PMC3587615?pdf=render

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