Rational design of antibiotic treatment plans: a treatment strategy for managing evolution and reversing resistance.

The development of reliable methods for restoring susceptibility after antibiotic resistance arises has proven elusive. A greater understanding of the relationship between antibiotic administration and the evolution of resistance is key to overcoming this challenge. Here we present a data-driven mat...

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Bibliographic Details
Main Authors: Portia M Mira, Kristina Crona, Devin Greene, Juan C Meza, Bernd Sturmfels, Miriam Barlow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4422678?pdf=render