Direct immunochemiluminescent assay for proBNP and total BNP in human plasma proBNP and total BNP levels in normal and heart failure.

Direct immunochemiluminescent assay for proBNP and total BNP in human plasma proBNP and total BNP levels in normal and heart failure.

BACKGROUND: Recent studies have shown that in addition to brain (or B-type) natriuretic peptide (BNP) and the N-terminal proBNP fragment, levels of intact proBNP are also increased in heart failure. Moreover, present BNP immunoassays also measure proBNP, as the anti-BNP antibody cross-reacts with pr...

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Bibliographic Details
Main Authors: Toshio Nishikimi, Hiroyuki Okamoto, Masahiro Nakamura, Naoko Ogawa, Kazukiyo Horii, Kiyoshi Nagata, Yasuaki Nakagawa, Hideyuki Kinoshita, Chinatsu Yamada, Kazuhiro Nakao, Takeya Minami, Yoshihiro Kuwabara, Koichiro Kuwahara, Izuru Masuda, Kenji Kangawa, Naoto Minamino, Kazuwa Nakao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3554706?pdf=render

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http://europepmc.org/articles/PMC3554706?pdf=render

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