High-level cross-resistance to didanosine observed in South African children failing an abacavir- or stavudine-based 1st-line regimen.

The knowledge-base of emerging drug resistance profiles in children exposed to abacavir-based antiretroviral regimens in South Africa is very limited. This study investigated the suitability of didanosine-based 2nd-line regimens for children in the context of antiretroviral drug resistance patterns...

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Bibliographic Details
Main Authors: Kim Steegen, Leon Levin, Irene Ketseoglou, Michelle Bronze, Maria A Papathanasopoulos, Sergio Carmona, Wendy Stevens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4016228?pdf=render